| Date | Location | Result | |
| 5/6/2022 | Lakewood, N.J. | Caldwell 6, Holy Family 3 | Box score |
| 5/5/2022 | Lakewood, N.J. | Holy Family 6, Post 2 | Box score |
| 5/5/2022 | Lakewood, N.J. | Georgian Court 5, Holy Family 1 | Box score |
| 4/30/2022 | Philadelphia, Pa. | Holy Family 2, Jefferson 0 | Box score |
| 4/30/2022 | Philadelphia, Pa. | Jefferson 6, Holy Family 1 | Box score |
| 4/26/2022 | Bensalem, Pa. | Holy Family 2, USciences 0 | Box score |
| 4/26/2022 | Bensalem, Pa. | USciences 9, Holy Family 4 | Box score |
| 4/25/2022 | Bensalem, Pa. | Holy Family 5, Chestnut Hill 3 | Box score |
| 4/25/2022 | Bensalem, Pa. | Holy Family 8, Chestnut Hill 0 | Box score |
| 4/24/2022 | Bensalem HS | Holy Family 1, Dominican (N.Y.) 0 | Box score |
| 4/24/2022 | Bensalem, Pa. | Holy Family 5, Dominican (N.Y.) 4 | Box score |
| 4/23/2022 | Wilmington, DE | Goldey-Beacom 10, Holy Family 5 | Box score |
| 4/23/2022 | Wilmington, DE | Holy Family 1, Goldey-Beacom 0 | Box score |
| 4/20/2022 | Bensalem, Pa. | Post 11, Holy Family 6 | Box score |
| 4/20/2022 | Bensalem, Pa. | Holy Family 7, Post 3 | Box score |
| 4/14/2022 | Bensalem, Pa. | Caldwell 13, Holy Family 4 | Box score |
| 4/14/2022 | Bensalem, Pa. | Caldwell 10, Holy Family 4 | Box score |
| 4/12/2022 | New Castle, Del. | Wilmington (Del.) 5, Holy Family 4 | Box score |
| 4/12/2022 | New Castle, Del. | Wilmington (Del.) 8, Holy Family 0 | Box score |
| 4/5/2022 | Bensalem HS | Shippensburg 10, Holy Family 2 | Box score |
| 4/5/2022 | Bensalem HS | Shippensburg 6, Holy Family 3 | Box score |
| 4/4/2022 | Bensalem HS | Georgian Court 7, Holy Family 3 | Box score |
| 4/4/2022 | Bensalem HS | Georgian Court 4, Holy Family 0 | Box score |
| 4/2/2022 | Wood-Ridge, N.J. | Felician 6, Holy Family 1 | Box score |
| 4/2/2022 | Wood-Ridge, N.J. | Felician 8, Holy Family 7 | Box score |
| 4/1/2022 | Staten Island, NY | Holy Family 9, Nyack 4 | Box score |
| 4/1/2022 | Staten Island, NY | Holy Family 11, Nyack 5 | Box score |
| 3/27/2022 | Bensalem, Pa. | Holy Family 9, Staten Island 8 | Box score |
| 3/26/2022 | Bensalem, Pa. | West Chester 7, Holy Family 1 | Box score |
| 3/26/2022 | Bensalem, Pa. | Holy Family 10, West Chester 9 | Box score |
| 03/21/22 | Little Ferry | Holy Family 10, Bloomfield 3 | Box score |
| 03/21/22 | Little Ferry | Bloomfield 11, Holy Family 4 | Box score |
| 03/20/22 | Bensalem, Pa. | Lock Haven 9, Holy Family 8 | Box score |
| 03/20/22 | Bensalem, Pa. | Lock Haven 9, Holy Family 1 | Box score |
| 03/16/22 | CSI | Staten Island 4, Holy Family 3 | Box score |
| 03/16/22 | CSI | Holy Family 6, Staten Island 5 | Box score |
| 03/15/22 | Bensalem, Pa. | East Stroudsburg 5, Holy Family 0 | Box score |
| 03/15/22 | Bensalem, Pa. | East Stroudsburg 7, Holy Family 0 | Box score |
| 03/05/22 | Winter Haven, Fla. | California (Pa.) 9, Holy Family 0 | Box score |
| 3/5/2022 | Winter Haven, FL | Ferris St. 9, Holy Family 1 | Box score |
| 03/04/22 | Winterhaven, Fla. | Sioux Falls 16, Holy Family 9 | Box score |
| 03/04/22 | Jan Phyl Village, FL | Assumption 7, Holy Family 3 | Box score |
| 03/03/22 | Winter Haven, Fla. | University of Mary 9, Holy Family 6 | Box score |
| 03/03/22 | Winter Haven, Fla. | Missouri - St. Louis 12, Holy Family 0 | Box score |
| 03/01/22 | Winter Haven, Fla. | Holy Family 3, Gannon 2 | Box score |
| 03/01/22 | Winter Haven, Fla. | Holy Family 4, Charleston 3 | Box score |
| 02/28/22 | Winter Haven, Fla. | Davenport 6, Holy Family 1 | Box score |
| 02/28/22 | Winter Haven | Bridgeport 6, Holy Family 0 | Box score |
| 02/27/22 | Winter Haven, Fla. | Findlay 11, Holy Family 0 | Box score |
| 02/27/22 | Winter Haven, Fla. | Tiffin 8, Holy Family 6 | Box score |